Correlation of Genetic and Physical Maps at the A Mating-Type Locus of Coprinus cinereus

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Correlation of genetic and physical maps at the A mating-type locus of Coprinus cinereus.

The A mating type locus of Coprinus cinereus is remarkable for its extreme diversity, with over 100 different alleles in natural populations. Classical genetic studies have demonstrated that this hypervariability arises in part from recombination between two subloci of A, alpha and beta, although more recent population genetic data have indicated a third segregating sublocus. In this study, we ...

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Recombination and Variation at the A Mating-Type of Coprinus cinereus

The molecular basis of variability at the Coprinus cinereus A mating-type was investigated. The A mating-type controls sexual compatibility in this basidiomycete fungus and, like the S loci of many plants, displays quite high levels of variation in natural populations. The A mating-type is a complex locus made up of a number of genes arranged in gene pairs. We determined the role of recombinati...

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The origin of multiple B mating specificities in Coprinus cinereus.

Mushrooms, such as Coprinus cinereus, possess large families of pheromones and G-protein-coupled receptors that are sequestered at the B mating-type locus and whose function is to confer vast numbers of different mating types. This ability results from complex patterns of cognate and noncognate pheromone/receptor pairings, which potentially offer a unique insight into the molecular interaction ...

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Molecular analysis of the Coprinus cinereus mating type A factor demonstrates an unexpectedly complex structure.

We report here the molecular cloning of the A43 mating type factor from Coprinus cinereus, a basidiomycetous fungus. Our molecular analyses revealed an unexpected source of variation in the A factor. Though genetic studies have demonstrated that A has two subunits, alpha and beta, we located three nonoverlapping fragments in the A43 region that have A factor function following DNA-mediated tran...

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ژورنال

عنوان ژورنال: Genetics

سال: 1996

ISSN: 1943-2631

DOI: 10.1093/genetics/144.4.1471